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Enhancement of ribosomal frameshifting by oligonucleotides targeted to the HIV gag-pol region.
The pol gene of all retroviruses is expressed as a gag-pol fusion protein which is proteolytically processed to produce all viral enzymes. In the human immunodeficiency virus (HIV), the gag and pol genes overlap by 241 nucleotides with pol in the -1 phase with respect to gag. The gag-pol fusion is p...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
1992
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC334071/ https://www.ncbi.nlm.nih.gov/pubmed/1508680 |