The R337H mutation in TP53 and breast cancer in Brazil

BACKGROUND: Germline mutations in p53 are associated with the Li-Fraumeni Syndrome which is characterized by childhood cancers, including pediatric adrenal cortical carcinomas and early onset breast cancer. The high incidence of adrenal cortical carcinomas in southern Brazil is mostly attributed to...

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Detalles Bibliográficos
Autores principales: Gomes, Magda CB, Kotsopoulos, Joanne, de Almeida, Gutemberg Leão, Costa, Mauricio M, Vieira, Roberto, Filho, Firmino de AG, Pitombo, Marcos B, F Leal, Paulo Roberto, Royer, Robert, Zhang, Phil, Narod, Steven A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341178/
https://www.ncbi.nlm.nih.gov/pubmed/22455664
http://dx.doi.org/10.1186/1897-4287-10-3

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