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Development of a Humanized Antibody with High Therapeutic Potential against Dengue Virus Type 2
BACKGROUND: Dengue virus (DENV) is a significant public health threat in tropical and subtropical regions of the world. A therapeutic antibody against the viral envelope (E) protein represents a promising immunotherapy for disease control. METHODOLOGY/PRINCIPAL FINDINGS: We generated seventeen novel...
Autores principales: | Li, Pi-Chun, Liao, Mei-Ying, Cheng, Ping-Chang, Liang, Jian-Jong, Liu, I-Ju, Chiu, Chien-Yu, Lin, Yi-Ling, Chang, Gwong-Jen J., Wu, Han-Chung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341331/ https://www.ncbi.nlm.nih.gov/pubmed/22563515 http://dx.doi.org/10.1371/journal.pntd.0001636 |
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