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Long Term Protection after Immunization with P. berghei Sporozoites Correlates with Sustained IFNγ Responses of Hepatic CD8+ Memory T Cells
Protection against P. berghei malaria can successfully be induced in mice by immunization with both radiation attenuated sporozoites (RAS) arresting early during liver stage development, or sporozoites combined with chloroquine chemoprophylaxis (CPS), resulting in complete intra-hepatic parasite dev...
Autores principales: | Nganou-Makamdop, Krystelle, van Gemert, Geert-Jan, Arens, Theo, Hermsen, Cornelus C., Sauerwein, Robert W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341355/ https://www.ncbi.nlm.nih.gov/pubmed/22563506 http://dx.doi.org/10.1371/journal.pone.0036508 |
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