Smooth Muscle Myosin Inhibition: A Novel Therapeutic Approach for Pulmonary Hypertension

OBJECTIVE: Pulmonary hypertension remains a major clinical problem despite current therapies. In this study, we examine for the first time a novel pharmacological target, smooth muscle myosin, and determine if the smooth muscle myosin inhibitor, CK-2019165 (CK-165) ameliorates pulmonary hypertension...

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Detalles Bibliográficos
Autores principales: Ho, David, Chen, Li, Zhao, Xin, Durham, Nicquanna, Pannirselvam, Malar, Vatner, Dorothy E., Morgans, David J., Malik, Fady I., Vatner, Stephen F., Shen, You-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341368/
https://www.ncbi.nlm.nih.gov/pubmed/22563487
http://dx.doi.org/10.1371/journal.pone.0036302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341368/
https://www.ncbi.nlm.nih.gov/pubmed/22563487
http://dx.doi.org/10.1371/journal.pone.0036302

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