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Pokeweed Antiviral Protein Increases HIV-1 Particle Infectivity by Activating the Cellular Mitogen Activated Protein Kinase Pathway

Pokeweed antiviral protein (PAP) is a plant-derived N-glycosidase that exhibits antiviral activity against several viruses. The enzyme removes purine bases from the messenger RNAs of the retroviruses Human immunodeficiency virus-1 and Human T-cell leukemia virus-1. This depurination reduces viral pr...

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Detalles Bibliográficos
Autores principales:	Mansouri, Sheila, Kutky, Meherzad, Hudak, Katalin A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341375/ https://www.ncbi.nlm.nih.gov/pubmed/22563495 http://dx.doi.org/10.1371/journal.pone.0036369

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