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Ghrelin Treatment of Cachectic Patients with Chronic Obstructive Pulmonary Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
BACKGROUND: Pulmonary cachexia is common in advanced chronic obstructive pulmonary disease (COPD), culminating in exercise intolerance and a poor prognosis. Ghrelin is a novel growth hormone (GH)-releasing peptide with GH-independent effects. The efficacy and safety of adding ghrelin to pulmonary re...
Autores principales: | Miki, Keisuke, Maekura, Ryoji, Nagaya, Noritoshi, Nakazato, Masamitsu, Kimura, Hiroshi, Murakami, Shinsuke, Ohnishi, Shunsuke, Hiraga, Toru, Miki, Mari, Kitada, Seigo, Yoshimura, Kenji, Tateishi, Yoshitaka, Arimura, Yasuji, Matsumoto, Nobuhiro, Yoshikawa, Masanori, Yamahara, Kenichi, Kangawa, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341383/ https://www.ncbi.nlm.nih.gov/pubmed/22563468 http://dx.doi.org/10.1371/journal.pone.0035708 |
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