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Rd9 Is a Naturally Occurring Mouse Model of a Common Form of Retinitis Pigmentosa Caused by Mutations in RPGR-ORF15
Animal models of human disease are an invaluable component of studies aimed at understanding disease pathogenesis and therapeutic possibilities. Mutations in the gene encoding retinitis pigmentosa GTPase regulator (RPGR) are the most common cause of X-linked retinitis pigmentosa (XLRP) and are estim...
Autores principales: | Thompson, Debra A., Khan, Naheed W., Othman, Mohammad I., Chang, Bo, Jia, Lin, Grahek, Garrett, Wu, Zhijian, Hiriyanna, Suja, Nellissery, Jacob, Li, Tiansen, Khanna, Hemant, Colosi, Peter, Swaroop, Anand, Heckenlively, John R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341386/ https://www.ncbi.nlm.nih.gov/pubmed/22563472 http://dx.doi.org/10.1371/journal.pone.0035865 |
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