Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5–17 months in Kenya and Tanzania: a randomised controlled trial

BACKGROUND: RTS,S/AS01E is the lead candidate malaria vaccine. We recently showed efficacy against clinical falciparum malaria in 5–17 month old children, during an average of 8 months follow-up. We aimed to assess the efficacy of RTS,S/AS01E during 15 months of follow-up. METHODS: Between March, 20...

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Detalles Bibliográficos
Autores principales: Olotu, Ally, Lusingu, John, Leach, Amanda, Lievens, Marc, Vekemans, Johan, Msham, Salum, Lang, Trudie, Gould, Jayne, Dubois, Marie-Claude, Jongert, Erik, Vansadia, Preeti, Carter, Terrell, Njuguna, Patricia, Awuondo, Ken O, Malabeja, Anangisye, Abdul, Omar, Gesase, Samwel, Mturi, Neema, Drakeley, Chris J, Savarese, Barbara, Villafana, Tonya, Lapierre, Didier, Ballou, W Ripley, Cohen, Joe, Lemnge, Martha M, Peshu, Norbert, Marsh, Kevin, Riley, Eleanor M, von Seidlein, Lorenz, Bejon, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science, The Lancet Pub. Group 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341451/
https://www.ncbi.nlm.nih.gov/pubmed/21237715
http://dx.doi.org/10.1016/S1473-3099(10)70262-0

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