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Risk factors for delayed recanalization of calf vein thrombosis
PURPOSE: To determine the risk factors of delayed recanalization of isolated calf vein thrombosis (CVT). METHODS: One hundred fifty limbs of 110 patients with CVT between September 2007 and April 2010 were enrolled. We used ultrasonography for the diagnosis and follow-up examinations of CVT. We calc...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Surgical Society
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341480/ https://www.ncbi.nlm.nih.gov/pubmed/22563538 http://dx.doi.org/10.4174/jkss.2012.82.5.306 |
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author | Park, Yang Jin Lee, Kyung-Bok Kim, Dong-Ik Roh, Young-Nam Kim, Nari Kim, Duk-Kyung Kim, Young-Wook |
author_facet | Park, Yang Jin Lee, Kyung-Bok Kim, Dong-Ik Roh, Young-Nam Kim, Nari Kim, Duk-Kyung Kim, Young-Wook |
author_sort | Park, Yang Jin |
collection | PubMed |
description | PURPOSE: To determine the risk factors of delayed recanalization of isolated calf vein thrombosis (CVT). METHODS: One hundred fifty limbs of 110 patients with CVT between September 2007 and April 2010 were enrolled. We used ultrasonography for the diagnosis and follow-up examinations of CVT. We calculated recanalization rates at 1 and 3 months after initial diagnosis and analyzed the risk factors associated with delayed recanalization of CVT. RESULTS: CVTs were located in the muscular calf vein in 110 (73.3%), in the deep calf vein in 18 (12%), and in both in 22 cases (14.7%). Among all CVTs, 94 limbs (63%) were symptomatic. Major risk factors for CVT were orthopedic surgery (87.3%), malignancy (21.3%), and immobilization (15.3%). Sixty-seven patients (60.9%) were treated with oral anticoagulation therapy, while 43 patients by low molecular weight heparin (n = 19) or by conservative methods including elastic compression stockings and ambulation (n = 21). The cumulative recanalization rate at 1 and 3 months was 23% and 82% and it was significantly higher in patients who underwent oral anticoagulation therapy compared with patients without oral anticoagulation therapy (84% vs. 65%, P = 0.008 by log-rank test). Malignancy (odds ratio [OR], 2.789; P = 0.043) and immobilization (OR, 4.191; P = 0.029) were independent risk factors for delayed recanalization of CVT and oral anticoagulation (OR, 0.300; P = 0.020) was an independent factor in promoting recanalization in multivariate analysis. CONCLUSION: For patients with isolated CVT, no oral anticoagulation resulted in higher rates of delayed recanalization compared to oral anticoagulation treatment. Immobilization and having malignancy were independent risk factors for delayed recanalization. |
format | Online Article Text |
id | pubmed-3341480 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | The Korean Surgical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-33414802012-05-04 Risk factors for delayed recanalization of calf vein thrombosis Park, Yang Jin Lee, Kyung-Bok Kim, Dong-Ik Roh, Young-Nam Kim, Nari Kim, Duk-Kyung Kim, Young-Wook J Korean Surg Soc Original Article PURPOSE: To determine the risk factors of delayed recanalization of isolated calf vein thrombosis (CVT). METHODS: One hundred fifty limbs of 110 patients with CVT between September 2007 and April 2010 were enrolled. We used ultrasonography for the diagnosis and follow-up examinations of CVT. We calculated recanalization rates at 1 and 3 months after initial diagnosis and analyzed the risk factors associated with delayed recanalization of CVT. RESULTS: CVTs were located in the muscular calf vein in 110 (73.3%), in the deep calf vein in 18 (12%), and in both in 22 cases (14.7%). Among all CVTs, 94 limbs (63%) were symptomatic. Major risk factors for CVT were orthopedic surgery (87.3%), malignancy (21.3%), and immobilization (15.3%). Sixty-seven patients (60.9%) were treated with oral anticoagulation therapy, while 43 patients by low molecular weight heparin (n = 19) or by conservative methods including elastic compression stockings and ambulation (n = 21). The cumulative recanalization rate at 1 and 3 months was 23% and 82% and it was significantly higher in patients who underwent oral anticoagulation therapy compared with patients without oral anticoagulation therapy (84% vs. 65%, P = 0.008 by log-rank test). Malignancy (odds ratio [OR], 2.789; P = 0.043) and immobilization (OR, 4.191; P = 0.029) were independent risk factors for delayed recanalization of CVT and oral anticoagulation (OR, 0.300; P = 0.020) was an independent factor in promoting recanalization in multivariate analysis. CONCLUSION: For patients with isolated CVT, no oral anticoagulation resulted in higher rates of delayed recanalization compared to oral anticoagulation treatment. Immobilization and having malignancy were independent risk factors for delayed recanalization. The Korean Surgical Society 2012-05 2012-04-26 /pmc/articles/PMC3341480/ /pubmed/22563538 http://dx.doi.org/10.4174/jkss.2012.82.5.306 Text en Copyright © 2012, the Korean Surgical Society http://creativecommons.org/licenses/by-nc/3.0 Journal of the Korean Surgical Society is an Open Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Park, Yang Jin Lee, Kyung-Bok Kim, Dong-Ik Roh, Young-Nam Kim, Nari Kim, Duk-Kyung Kim, Young-Wook Risk factors for delayed recanalization of calf vein thrombosis |
title | Risk factors for delayed recanalization of calf vein thrombosis |
title_full | Risk factors for delayed recanalization of calf vein thrombosis |
title_fullStr | Risk factors for delayed recanalization of calf vein thrombosis |
title_full_unstemmed | Risk factors for delayed recanalization of calf vein thrombosis |
title_short | Risk factors for delayed recanalization of calf vein thrombosis |
title_sort | risk factors for delayed recanalization of calf vein thrombosis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341480/ https://www.ncbi.nlm.nih.gov/pubmed/22563538 http://dx.doi.org/10.4174/jkss.2012.82.5.306 |
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