The Gain of Function of p53 Mutant p53S in Promoting Tumorigenesis by Cross-talking with H-RasV12

The loss of wild type p53 tumor suppressive function and oncogenic gain-of-function of p53 mutants have been showing important implications in tumorigenesis. The p53(N236S) (p53(N239S) in human, p53S) mutation has been shown to lose wild type p53 function by yeast assay. However, its gain of functio...

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Detalles Bibliográficos
Autores principales: Jia, Shuting, Zhao, Lanjun, Tang, Wenru, Luo, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341601/
https://www.ncbi.nlm.nih.gov/pubmed/22553460
http://dx.doi.org/10.7150/ijbs.4176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341601/
https://www.ncbi.nlm.nih.gov/pubmed/22553460
http://dx.doi.org/10.7150/ijbs.4176

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