Cargando…

Amino Acid Position 11 of HLA-DRβ1 is a Major Determinant of Chromosome 6p Association with Ulcerative Colitis

The major histocompatibility complex (MHC) on chromosome 6p is an established risk locus for ulcerative colitis (UC) and Crohn’s disease (CD). We aimed to better define MHC association signals in UC and CD by combining data from dense single nucleotide polymorphism (SNP) genotyping and from imputati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Achkar, Jean-Paul, Klei, Lambertus, de Bakker, Paul I.W., Bellone, Gaia, Rebert, Nancy, Scott, Regan, Lu, Ying, Regueiro, Miguel, Brzezinski, Aaron, Kamboh, M. Ilyas, Fiocchi, Claudio, Devlin, Bernie, Trucco, Massimo, Ringquist, Steven, Roeder, Kathryn, Duerr, Richard H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341846/ https://www.ncbi.nlm.nih.gov/pubmed/22170232 http://dx.doi.org/10.1038/gene.2011.79

Ejemplares similares

Clustering and Alignment of Polymorphic Sequences for HLA-DRB1 Genotyping
por: Ringquist, Steven, et al.
Publicado: (2013)

Semisoft clustering of single-cell data
por: Zhu, Lingxue, et al.
Publicado: (2019)

Functional connectome fingerprinting accuracy in youths and adults is similar when examined on the same day and 1.5‐years apart
por: Jalbrzikowski, Maria, et al.
Publicado: (2020)

O11.1. MULTIPLE GENOMIC MEASURES OF SCHIZOPHRENIA RISK ARE RELATED TO CORTICAL THICKNESS IN TYPICALLY DEVELOPING YOUTH AND YOUNG ADULTS
por: Jalbrzikowski, Maria, et al.
Publicado: (2020)

Novel Genetic Risk Variants and Clinical Predictors Associated With Primary Sclerosing Cholangitis in Patients With Ulcerative Colitis
por: Wang, Ming-Hsi, et al.
Publicado: (2023)

Heritable Variation, With Little or No Maternal Effect, Accounts for Recurrence Risk to Autism Spectrum Disorder in Sweden
por: Yip, Benjamin Hon Kei, et al.
Publicado: (2017)

Using multiple measurements of tissue to estimate subject- and cell-type-specific gene expression
por: Wang, Jiebiao, et al.
Publicado: (2020)

Bayesian estimation of cell type–specific gene expression with prior derived from single-cell data
por: Wang, Jiebiao, et al.
Publicado: (2021)

Ulcerative colitis loci on chromosomes 1p36 and 12q15 identified by genome-wide association study
por: Silverberg, Mark S., et al.
Publicado: (2009)

Intelligence, genes, and success: scientists respond to the bell curve
por: Devlin, Bernie, et al.
Publicado: (1997)

Integration of association statistics over genomic regions using Bayesian adaptive regression splines
por: Zhang, Xiaohua, et al.
Publicado: (2003)

Comparison of gene expression in living and postmortem human brain
por: Collado-Torres, Leonardo, et al.
Publicado: (2023)

A selective inference approach for false discovery rate control using multiomics covariates yields insights into disease risk
por: Yurko, Ronald, et al.
Publicado: (2020)

Transcriptome alterations are enriched for synapse-associated genes in the striatum of subjects with obsessive-compulsive disorder
por: Piantadosi, Sean C., et al.
Publicado: (2021)

Genetic Risk for Schizophrenia and Psychosis in Alzheimer Disease
por: DeMichele-Sweet, Mary Ann A., et al.
Publicado: (2017)

Prevalence and phenotypic impact of rare potentially damaging variants in autism spectrum disorder
por: Mahjani, Behrang, et al.
Publicado: (2021)

How rare and common risk variation jointly affect liability for autism spectrum disorder
por: Klei, Lambertus, et al.
Publicado: (2021)

Next-generation sequencing for HLA typing of class I loci
por: Erlich, Rachel L, et al.
Publicado: (2011)

Schizophrenia-associated differential DNA methylation in brain is distributed across the genome and annotated to MAD1L1, a locus at which DNA methylation and transcription phenotypes share genetic variation with schizophrenia risk
por: McKinney, Brandon C., et al.
Publicado: (2022)

Classical HLA-DRB1 and DPB1 Alleles Account for HLA Associations with Primary Biliary Cirrhosis
por: Invernizzi, Pietro, et al.
Publicado: (2012)

De novo missense variants disrupting protein–protein interactions affect risk for autism through gene co-expression and protein networks in neuronal cell types
por: Chen, Siwei, et al.
Publicado: (2020)

PTGER4 Expression-Modulating Polymorphisms in the 5p13.1 Region Predispose to Crohn's Disease and Affect NF-κB and XBP1 Binding Sites
por: Glas, Jürgen, et al.
Publicado: (2012)

Most genetic risk for autism resides with common variation
por: Gaugler, Trent, et al.
Publicado: (2014)

The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment
por: Cotney, Justin, et al.
Publicado: (2015)

SOP(3)v2: web-based selection of oligonucleotide primer trios for genotyping of human and mouse polymorphisms
por: Ringquist, Steven, et al.
Publicado: (2005)

A Brief Synopsis on the Genetics of Alzheimer’s Disease
por: Kamboh, M. Ilyas
Publicado: (2018)

Genomics and Functional Genomics of Alzheimer’s Disease
por: Kamboh, M. Ilyas
Publicado: (2021)

DAWN: a framework to identify autism genes and subnetworks using gene expression and genetics
por: Liu, Li, et al.
Publicado: (2014)

Late-Onset Alzheimer’s Disease Genes and the Potentially Implicated Pathways
por: Rosenthal, Samantha L., et al.
Publicado: (2014)

Principal Components of Heritability From Neurocognitive Domains Differ Between Families With Schizophrenia and Control Subjects
por: Wiener, Howard, et al.
Publicado: (2013)

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
por: Raychaudhuri, Soumya, et al.
Publicado: (2012)

A novel murine model of pyoderma gangrenosum reveals that inflammatory skin-gut crosstalk is mediated by IL-1β-primed neutrophils
por: Jatana, Samreen, et al.
Publicado: (2023)

Shedding new light on genetic dark matter
por: Melhem, Nadine, et al.
Publicado: (2010)

Sterile subconjunctival abscess in an HLA-B51-positive patient with ulcerative colitis
por: Kukimoto, Nobuyuki, et al.
Publicado: (2021)

Population-Based Resequencing of LIPG and ZNF202 Genes in Subjects with Extreme HDL Levels
por: Razzaghi, Hamid, et al.
Publicado: (2012)

Proficiency of data interpretation: identification of signaling SNPs/specific loci for coronary artery disease
por: Cheema, Asma N, et al.
Publicado: (2017)

Comparative modelling by restraint-based conformational sampling
por: Furnham, Nicholas, et al.
Publicado: (2008)

Association between Takayasu arteritis and ulcerative colitis – case report and review of serological HLA analysis
por: Takahashi, Nobuyuki, et al.
Publicado: (2011)

Association between KIR-HLA combination and ulcerative colitis and Crohn’s disease in a Japanese population
por: Saito, Hiromi, et al.
Publicado: (2018)

HLA-DQA1*05 Associates with Extensive Ulcerative Colitis at Diagnosis: An Observational Study in Children
por: Nowak, Jan Krzysztof, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_11cuslab4bdlqhjjve5egvktev