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PI3K/Akt signalling is required for the attachment and spreading, and growth in vivo of metastatic scirrhous gastric carcinoma
BACKGROUND: PI3K/Akt (PKB) pathway has been shown in several cell types to be activated by ligands to cell surface integrins, leading to the metastasis of tumour cells. The signalling pathways involved in the metastatic spread of human scirrhous gastric carcinoma cells have not been defined. METHODS...
Autores principales: | Matsuoka, T, Yashiro, M, Nishioka, N, Hirakawa, K, Olden, K, Roberts, J D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341864/ https://www.ncbi.nlm.nih.gov/pubmed/22531720 http://dx.doi.org/10.1038/bjc.2012.107 |
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