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Molecular Mechanisms of Treg-Mediated T Cell Suppression
CD4(+)CD25(high)Foxp3(+) regulatory T cells (Tregs) can suppress other immune cells and, thus, are critical mediators of peripheral self-tolerance. On the one hand, Tregs avert autoimmune disease and allergies. On the other hand, Tregs can prevent immune reactions against tumors and pathogens. Despi...
Autores principales: | Schmidt, Angelika, Oberle, Nina, Krammer, Peter H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341960/ https://www.ncbi.nlm.nih.gov/pubmed/22566933 http://dx.doi.org/10.3389/fimmu.2012.00051 |
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