Generation and Characterization of Anti-AA Amyloid-Specific Monoclonal Antibodies

AA amyloidosis results from the pathologic deposition in the kidneys and other organs of fibrils composed of N-terminal fragments of serum amyloid A protein (SAA). Given that there are only limited means to visualize these deposits, we have developed a series of mAbs, 2A4, 7D8, and 8G9, that bind sp...

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Detalles Bibliográficos
Autores principales: Wall, Jonathan S., Kennel, Stephen J., Richey, Tina, Allen, Amy, Stuckey, Alan, Weiss, Deborah T., Macy, Sallie D., Barbour, Robin, Seubert, Peter, Solomon, Alan, Schenk, Dale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341974/
https://www.ncbi.nlm.nih.gov/pubmed/22566822
http://dx.doi.org/10.3389/fimmu.2011.00032

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