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Selection of Mesenchymal-Like Metastatic Cells in Primary Tumors – An in silico Investigation

In order to metastasize, cancer cells must undergo phenotypic transition from an anchorage-dependent form to a motile form via a process referred to as epithelial to mesenchymal transition. It is currently unclear whether metastatic cells emerge late during tumor progression by successive accumulati...

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Detalles Bibliográficos
Autores principales: Narang, Vipin, Wong, Shek Yoon, Leong, Shiang Rong, Harish, Bindu, Abastado, Jean-Pierre, Gouaillard, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342023/
https://www.ncbi.nlm.nih.gov/pubmed/22566967
http://dx.doi.org/10.3389/fimmu.2012.00088