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Selection of Mesenchymal-Like Metastatic Cells in Primary Tumors – An in silico Investigation
In order to metastasize, cancer cells must undergo phenotypic transition from an anchorage-dependent form to a motile form via a process referred to as epithelial to mesenchymal transition. It is currently unclear whether metastatic cells emerge late during tumor progression by successive accumulati...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342023/ https://www.ncbi.nlm.nih.gov/pubmed/22566967 http://dx.doi.org/10.3389/fimmu.2012.00088 |