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The Human C1q Globular Domain: Structure and Recognition of Non-Immune Self Ligands

C1q, the ligand-binding unit of the C1 complex of complement, is a pattern recognition molecule with the unique ability to sense an amazing variety of targets, including a number of altered structures from self, such as apoptotic cells. The three-dimensional structure of its C-terminal globular doma...

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Detalles Bibliográficos
Autores principales: Gaboriaud, Christine, Frachet, Philippe, Thielens, Nicole M., Arlaud, Gérard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342031/
https://www.ncbi.nlm.nih.gov/pubmed/22566881
http://dx.doi.org/10.3389/fimmu.2011.00092