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Insights into T Cell Recognition of Antigen: Significance of Two-Dimensional Kinetic Parameters

The T cell receptor (TCR) interacts with peptide-major histocompatibility complex (pMHC) to enable T cell development and trigger adaptive immune responses. For this reason, TCR:pMHC interactions have been intensely studied for over two decades. However, the details of how various binding parameters...

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Detalles Bibliográficos
Autores principales:	Edwards, Lindsay J., Zarnitsyna, Veronika I., Hood, Jennifer D., Evavold, Brian D., Zhu, Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342060/ https://www.ncbi.nlm.nih.gov/pubmed/22566966 http://dx.doi.org/10.3389/fimmu.2012.00086

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