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Differential Role of “Signal 3” Inflammatory Cytokines in Regulating CD8 T Cell Expansion and Differentiation in vivo

Following an infection, naïve CD8 T cells are stimulated by dendritic cells (DC) displaying pathogen-derived peptides on MHC class I molecules (signal 1) and costimulatory molecules (signal 2). Additionally, pathogen-induced inflammatory cytokines also act directly on the responding CD8 T cells to r...

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Detalles Bibliográficos
Autores principales:	Pham, Nhat-Long L., Badovinac, Vladimir P., Harty, John T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2011
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342074/ https://www.ncbi.nlm.nih.gov/pubmed/22566795 http://dx.doi.org/10.3389/fimmu.2011.00004

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