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Bilateral multifocal Warthin's tumors in upper neck lymph nodes. report of a case and brief review of the literature
Cystadenolymphomas (Warthin's tumors) are the second most frequent lesions of the parotid gland. Due to their benign clinical behavior, the low rates of recurrence and malignant transformation they were classified as tumor-like lesions. In addition, a polyclonal growth of the epithelial compone...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342104/ https://www.ncbi.nlm.nih.gov/pubmed/22472434 http://dx.doi.org/10.1186/1746-160X-8-11 |
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author | Naujoks, Christian Sproll, Christoph Singh, Daman Deep Heikaus, Sebastian Depprich, Rita Kübler, Norbert R Handschel, Jörg |
author_facet | Naujoks, Christian Sproll, Christoph Singh, Daman Deep Heikaus, Sebastian Depprich, Rita Kübler, Norbert R Handschel, Jörg |
author_sort | Naujoks, Christian |
collection | PubMed |
description | Cystadenolymphomas (Warthin's tumors) are the second most frequent lesions of the parotid gland. Due to their benign clinical behavior, the low rates of recurrence and malignant transformation they were classified as tumor-like lesions. In addition, a polyclonal growth of the epithelial components of the tumor could be detected. Warthin's tumors occur bilateral in 7-10%, whereas a multifocal appearance is extremely rare. Even if the pathogenesis is still unclear a heterotopia of salivary tissue during embryogenesis is the most likely explanation for the origin of these tumors in the upper neck and periparotideal region. Here we present a rare case of bilateral, multifocal, extraglandular Warthin's tumors in lymph nodes of the upper neck and give a brief review of the literature. If a primary malignancy can be excluded by a careful staging procedure prior to the operation an isolated excision of the lesions of the neck is the adequate treatment. |
format | Online Article Text |
id | pubmed-3342104 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-33421042012-05-03 Bilateral multifocal Warthin's tumors in upper neck lymph nodes. report of a case and brief review of the literature Naujoks, Christian Sproll, Christoph Singh, Daman Deep Heikaus, Sebastian Depprich, Rita Kübler, Norbert R Handschel, Jörg Head Face Med Case Report Cystadenolymphomas (Warthin's tumors) are the second most frequent lesions of the parotid gland. Due to their benign clinical behavior, the low rates of recurrence and malignant transformation they were classified as tumor-like lesions. In addition, a polyclonal growth of the epithelial components of the tumor could be detected. Warthin's tumors occur bilateral in 7-10%, whereas a multifocal appearance is extremely rare. Even if the pathogenesis is still unclear a heterotopia of salivary tissue during embryogenesis is the most likely explanation for the origin of these tumors in the upper neck and periparotideal region. Here we present a rare case of bilateral, multifocal, extraglandular Warthin's tumors in lymph nodes of the upper neck and give a brief review of the literature. If a primary malignancy can be excluded by a careful staging procedure prior to the operation an isolated excision of the lesions of the neck is the adequate treatment. BioMed Central 2012-04-03 /pmc/articles/PMC3342104/ /pubmed/22472434 http://dx.doi.org/10.1186/1746-160X-8-11 Text en Copyright ©2012 Naujoks et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Naujoks, Christian Sproll, Christoph Singh, Daman Deep Heikaus, Sebastian Depprich, Rita Kübler, Norbert R Handschel, Jörg Bilateral multifocal Warthin's tumors in upper neck lymph nodes. report of a case and brief review of the literature |
title | Bilateral multifocal Warthin's tumors in upper neck lymph nodes. report of a case and brief review of the literature |
title_full | Bilateral multifocal Warthin's tumors in upper neck lymph nodes. report of a case and brief review of the literature |
title_fullStr | Bilateral multifocal Warthin's tumors in upper neck lymph nodes. report of a case and brief review of the literature |
title_full_unstemmed | Bilateral multifocal Warthin's tumors in upper neck lymph nodes. report of a case and brief review of the literature |
title_short | Bilateral multifocal Warthin's tumors in upper neck lymph nodes. report of a case and brief review of the literature |
title_sort | bilateral multifocal warthin's tumors in upper neck lymph nodes. report of a case and brief review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342104/ https://www.ncbi.nlm.nih.gov/pubmed/22472434 http://dx.doi.org/10.1186/1746-160X-8-11 |
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