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High-throughput detection of aberrant imprint methylation in the ovarian cancer by the bisulphite PCR-Luminex method
BACKGROUND: Aberrant DNA methylation leads to loss of heterozygosity (LOH) or loss of imprinting (LOI) as the first hit during human carcinogenesis. Recently we developed a new high-throughput, high-resolution DNA methylation analysis method, bisulphite PCR-Luminex (BPL), using sperm DNA and demonst...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342152/ https://www.ncbi.nlm.nih.gov/pubmed/22443985 http://dx.doi.org/10.1186/1755-8794-5-8 |