Quantitative analysis of water distribution in human articular cartilage using terahertz time-domain spectroscopy

The water distribution in human osteoarthritic articular cartilage has been quantitatively characterized using terahertz time-domain spectroscopy (THz TDS). We measured the refractive index and absorption coefficient of cartilage tissue in the THz frequency range. Based on our measurements, the esti...

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Detalles Bibliográficos
Autores principales: Jung, Euna, Choi, Hyuck Jae, Lim, Meehyun, Kang, Hyeona, Park, Hongkyu, Han, Haewook, Min, Byung-hyun, Kim, Sangin, Park, Ikmo, Lim, Hanjo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2012
Materias:
Spectroscopic Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342186/
https://www.ncbi.nlm.nih.gov/pubmed/22567600
http://dx.doi.org/10.1364/BOE.3.001110
Descripción
Sumario:The water distribution in human osteoarthritic articular cartilage has been quantitatively characterized using terahertz time-domain spectroscopy (THz TDS). We measured the refractive index and absorption coefficient of cartilage tissue in the THz frequency range. Based on our measurements, the estimated water content was observed to decrease with increasing depth cartilage tissue, showing good agreement with a previous report based on destructive biochemical methods.

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