Quantitative analysis of water distribution in human articular cartilage using terahertz time-domain spectroscopy

The water distribution in human osteoarthritic articular cartilage has been quantitatively characterized using terahertz time-domain spectroscopy (THz TDS). We measured the refractive index and absorption coefficient of cartilage tissue in the THz frequency range. Based on our measurements, the esti...

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Autores principales: Jung, Euna, Choi, Hyuck Jae, Lim, Meehyun, Kang, Hyeona, Park, Hongkyu, Han, Haewook, Min, Byung-hyun, Kim, Sangin, Park, Ikmo, Lim, Hanjo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2012
Materias:
Spectroscopic Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342186/
https://www.ncbi.nlm.nih.gov/pubmed/22567600
http://dx.doi.org/10.1364/BOE.3.001110
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author Jung, Euna
Choi, Hyuck Jae
Lim, Meehyun
Kang, Hyeona
Park, Hongkyu
Han, Haewook
Min, Byung-hyun
Kim, Sangin
Park, Ikmo
Lim, Hanjo
author_facet Jung, Euna
Choi, Hyuck Jae
Lim, Meehyun
Kang, Hyeona
Park, Hongkyu
Han, Haewook
Min, Byung-hyun
Kim, Sangin
Park, Ikmo
Lim, Hanjo
author_sort Jung, Euna
collection PubMed
description The water distribution in human osteoarthritic articular cartilage has been quantitatively characterized using terahertz time-domain spectroscopy (THz TDS). We measured the refractive index and absorption coefficient of cartilage tissue in the THz frequency range. Based on our measurements, the estimated water content was observed to decrease with increasing depth cartilage tissue, showing good agreement with a previous report based on destructive biochemical methods.
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spelling pubmed-33421862012-05-07 Quantitative analysis of water distribution in human articular cartilage using terahertz time-domain spectroscopy Jung, Euna Choi, Hyuck Jae Lim, Meehyun Kang, Hyeona Park, Hongkyu Han, Haewook Min, Byung-hyun Kim, Sangin Park, Ikmo Lim, Hanjo Biomed Opt Express Spectroscopic Diagnostics The water distribution in human osteoarthritic articular cartilage has been quantitatively characterized using terahertz time-domain spectroscopy (THz TDS). We measured the refractive index and absorption coefficient of cartilage tissue in the THz frequency range. Based on our measurements, the estimated water content was observed to decrease with increasing depth cartilage tissue, showing good agreement with a previous report based on destructive biochemical methods. Optical Society of America 2012-04-25 /pmc/articles/PMC3342186/ /pubmed/22567600 http://dx.doi.org/10.1364/BOE.3.001110 Text en ©2012 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Spectroscopic Diagnostics
Jung, Euna
Choi, Hyuck Jae
Lim, Meehyun
Kang, Hyeona
Park, Hongkyu
Han, Haewook
Min, Byung-hyun
Kim, Sangin
Park, Ikmo
Lim, Hanjo
Quantitative analysis of water distribution in human articular cartilage using terahertz time-domain spectroscopy
title Quantitative analysis of water distribution in human articular cartilage using terahertz time-domain spectroscopy
title_full Quantitative analysis of water distribution in human articular cartilage using terahertz time-domain spectroscopy
title_fullStr Quantitative analysis of water distribution in human articular cartilage using terahertz time-domain spectroscopy
title_full_unstemmed Quantitative analysis of water distribution in human articular cartilage using terahertz time-domain spectroscopy
title_short Quantitative analysis of water distribution in human articular cartilage using terahertz time-domain spectroscopy
title_sort quantitative analysis of water distribution in human articular cartilage using terahertz time-domain spectroscopy
topic Spectroscopic Diagnostics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342186/
https://www.ncbi.nlm.nih.gov/pubmed/22567600
http://dx.doi.org/10.1364/BOE.3.001110
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