Cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope

Microscopy with nonlinear phase contrast is achieved by a simple modification to a nonlinear pump-probe microscope. The technique measures cross-phase modulation by detecting a pump-induced spectral shift in the probe pulse. Images with nonlinear phase contrast are acquired both in transparent and a...

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Detalles Bibliográficos
Autores principales: Wilson, Jesse W., Samineni, Prathyush, Warren, Warren S., Fischer, Martin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2012
Materias:
Microscopy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342192/
https://www.ncbi.nlm.nih.gov/pubmed/22567580
http://dx.doi.org/10.1364/BOE.3.000854
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author Wilson, Jesse W.
Samineni, Prathyush
Warren, Warren S.
Fischer, Martin C.
author_facet Wilson, Jesse W.
Samineni, Prathyush
Warren, Warren S.
Fischer, Martin C.
author_sort Wilson, Jesse W.
collection PubMed
description Microscopy with nonlinear phase contrast is achieved by a simple modification to a nonlinear pump-probe microscope. The technique measures cross-phase modulation by detecting a pump-induced spectral shift in the probe pulse. Images with nonlinear phase contrast are acquired both in transparent and absorptive media. In paraffin-embedded biopsy sections, cross-phase modulation complements the chemically-specific pump-probe images with structural context.
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spelling pubmed-33421922012-05-07 Cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope Wilson, Jesse W. Samineni, Prathyush Warren, Warren S. Fischer, Martin C. Biomed Opt Express Microscopy Microscopy with nonlinear phase contrast is achieved by a simple modification to a nonlinear pump-probe microscope. The technique measures cross-phase modulation by detecting a pump-induced spectral shift in the probe pulse. Images with nonlinear phase contrast are acquired both in transparent and absorptive media. In paraffin-embedded biopsy sections, cross-phase modulation complements the chemically-specific pump-probe images with structural context. Optical Society of America 2012-04-04 /pmc/articles/PMC3342192/ /pubmed/22567580 http://dx.doi.org/10.1364/BOE.3.000854 Text en ©2012 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Microscopy
Wilson, Jesse W.
Samineni, Prathyush
Warren, Warren S.
Fischer, Martin C.
Cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope
title Cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope
title_full Cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope
title_fullStr Cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope
title_full_unstemmed Cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope
title_short Cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope
title_sort cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope
topic Microscopy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342192/
https://www.ncbi.nlm.nih.gov/pubmed/22567580
http://dx.doi.org/10.1364/BOE.3.000854
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