Systematic Analysis of Cell Cycle Effects of Common Drugs Leads to the Discovery of a Suppressive Interaction between Gemfibrozil and Fluoxetine

Screening chemical libraries to identify compounds that affect overall cell proliferation is common. However, in most cases, it is not known whether the compounds tested alter the timing of particular cell cycle transitions. Here, we evaluated an FDA-approved drug library to identify pharmaceuticals...

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Detalles Bibliográficos
Autores principales: Hoose, Scott A., Duran, Camille, Malik, Indranil, Eslamfam, Shabnam, Shasserre, Samantha C., Downing, S. Sabina, Hoover, Evelyn M., Dowd, Katherine E., Smith, Roger, Polymenis, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342239/
https://www.ncbi.nlm.nih.gov/pubmed/22567160
http://dx.doi.org/10.1371/journal.pone.0036503

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