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Do Anti-Angiogenic VEGF (VEGFxxxb) Isoforms Exist? A Cautionary Tale

Splicing of the human vascular endothelial growth factor-A (VEGF-A) gene has been reported to generate angiogenic (VEGFxxx) and anti-angiogenic (VEGFxxxb) isoforms. Corresponding VEGFxxxb isoforms have also been reported in rat and mouse. We examined VEGFxxxb expression in mouse fibrosarcoma cell li...

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Detalles Bibliográficos
Autores principales: Harris, Sheila, Craze, Madeleine, Newton, Jillian, Fisher, Matthew, Shima, David T., Tozer, Gillian M., Kanthou, Chryso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342274/
https://www.ncbi.nlm.nih.gov/pubmed/22567098
http://dx.doi.org/10.1371/journal.pone.0035231