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TCR Mechanobiology: Torques and Tunable Structures Linked to Early T Cell Signaling

Mechanotransduction is a basis for receptor signaling in many biological systems. Recent data based upon optical tweezer experiments suggest that the TCR is an anisotropic mechanosensor, converting mechanical energy into biochemical signals upon specific peptide-MHC complex (pMHC) ligation. Tangenti...

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Detalles Bibliográficos
Autores principales:	Kim, Sun Taek, Shin, Yongdae, Brazin, Kristine, Mallis, Robert J., Sun, Zhen-Yu J., Wagner, Gerhard, Lang, Matthew J., Reinherz, Ellis L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342345/ https://www.ncbi.nlm.nih.gov/pubmed/22566957 http://dx.doi.org/10.3389/fimmu.2012.00076

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