PID Comes Full Circle: Applications of V(D)J Recombination Excision Circles in Research, Diagnostics and Newborn Screening of Primary Immunodeficiency Disorders

The vast majority of patients suffering from a primary immunodeficiency (PID) have defects in their T- and/or B-cell compartments. Despite advances in molecular diagnostics, in many patients no underlying genetic defect has been identified. B- and T-lymphocytes are unique in their ability to create...

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Detalles Bibliográficos
Autores principales: van Zelm, Menno C., van der Burg, Mirjam, Langerak, Anton W., van Dongen, Jacques J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342366/
https://www.ncbi.nlm.nih.gov/pubmed/22566803
http://dx.doi.org/10.3389/fimmu.2011.00012

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