Loss-of-Function of Gli3 in Mice Causes Abnormal Frontal Bone Morphology and Premature Synostosis of the Interfrontal Suture

Greig cephalopolysyndactyly syndrome (GCPS) is an autosomal dominant disorder with polydactyly and syndactyly of the limbs and a broad spectrum of craniofacial abnormalities. Craniosynostosis of the metopic suture (interfrontal suture in mice) is an important but rare feature associated with GCPS. G...

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Detalles Bibliográficos
Autores principales: Veistinen, Lotta, Takatalo, Maarit, Tanimoto, Yukiho, Kesper, Dörthe A., Vortkamp, Andrea, Rice, David P. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342524/
https://www.ncbi.nlm.nih.gov/pubmed/22563320
http://dx.doi.org/10.3389/fphys.2012.00121

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