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Serum osteoprotegerin is increased and predicts survival in idiopathic pulmonary arterial hypertension

We previously reported that osteoprotegerin (OPG) is regulated by pathways associated with pulmonary arterial hypertension (PAH), and is present at elevated levels within pulmonary vascular lesions and sera from patients with idiopathic PAH (IPAH). Since OPG is a naturally secreted protein, we inves...

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Detalles Bibliográficos
Autores principales: Condliffe, Robin, Pickworth, Josephine A., Hopkinson, Kay, Walker, Sara J., Hameed, Abdul G., Suntharaligam, Jay, Soon, Elaine, Treacy, Carmen, Pepke-Zaba, Joanna, Francis, Sheila E., Crossman, David C., Newman, Christopher M. H., Elliot, Charles A., Morton, Allison C., Morrell, Nicholas W., Kiely, David G., Lawrie, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342744/
https://www.ncbi.nlm.nih.gov/pubmed/22558516
http://dx.doi.org/10.4103/2045-8932.94819

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