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Experimental Analysis of Sources of Error in Evolutionary Studies Based on Roche/454 Pyrosequencing of Viral Genomes

Factors affecting the reliability of Roche/454 pyrosequencing for analyzing sequence polymorphism in within-host viral populations were assessed by two experiments: 1) sequencing four clonal simian immunodeficiency virus (SIV) stocks and 2) sequencing mixtures in different proportions of two SIV str...

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Detalles Bibliográficos
Autores principales:	Becker, Ericka A., Burns, Charles M., León, Enrique J., Rajabojan, Saravanan, Friedman, Robert, Friedrich, Thomas C., O'Connor, Shelby L., Hughes, Austin L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342875/ https://www.ncbi.nlm.nih.gov/pubmed/22436995 http://dx.doi.org/10.1093/gbe/evs029

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