The clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter?

Tumor infiltrating lymphocytes (TILs) are commonly detected in breast tumors but their bearing on disease outcome is uncertain. The importance of TILs appears to be subtype-specific and varies depending on the histologic characteristics of the tumor. As our understanding of tumorigenesis is increasi...

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Detalles Bibliográficos
Autores principales: Krell, Jonathan, Frampton, Adam E, Stebbing, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342888/
https://www.ncbi.nlm.nih.gov/pubmed/22471994
http://dx.doi.org/10.1186/1471-2407-12-135
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author Krell, Jonathan
Frampton, Adam E
Stebbing, Justin
author_facet Krell, Jonathan
Frampton, Adam E
Stebbing, Justin
author_sort Krell, Jonathan
collection PubMed
description Tumor infiltrating lymphocytes (TILs) are commonly detected in breast tumors but their bearing on disease outcome is uncertain. The importance of TILs appears to be subtype-specific and varies depending on the histologic characteristics of the tumor. As our understanding of tumorigenesis is increasing the relevance of immunobiology will become apparent.
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spelling pubmed-33428882012-05-04 The clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter? Krell, Jonathan Frampton, Adam E Stebbing, Justin BMC Cancer Commentary Tumor infiltrating lymphocytes (TILs) are commonly detected in breast tumors but their bearing on disease outcome is uncertain. The importance of TILs appears to be subtype-specific and varies depending on the histologic characteristics of the tumor. As our understanding of tumorigenesis is increasing the relevance of immunobiology will become apparent. BioMed Central 2012-04-03 /pmc/articles/PMC3342888/ /pubmed/22471994 http://dx.doi.org/10.1186/1471-2407-12-135 Text en Copyright ©2012 Krell et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Krell, Jonathan
Frampton, Adam E
Stebbing, Justin
The clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter?
title The clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter?
title_full The clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter?
title_fullStr The clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter?
title_full_unstemmed The clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter?
title_short The clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter?
title_sort clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342888/
https://www.ncbi.nlm.nih.gov/pubmed/22471994
http://dx.doi.org/10.1186/1471-2407-12-135
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