The Lipopolysaccharide from Capnocytophaga canimorsus Reveals an Unexpected Role of the Core-Oligosaccharide in MD-2 Binding

Capnocytophaga canimorsus is a usual member of dog's mouths flora that causes rare but dramatic human infections after dog bites. We determined the structure of C. canimorsus lipid A. The main features are that it is penta-acylated and composed of a “hybrid backbone” lacking the 4′ phosphate an...

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Detalles Bibliográficos
Autores principales: Ittig, Simon, Lindner, Buko, Stenta, Marco, Manfredi, Pablo, Zdorovenko, Evelina, Knirel, Yuriy A., dal Peraro, Matteo, Cornelis, Guy R., Zähringer, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342949/
https://www.ncbi.nlm.nih.gov/pubmed/22570611
http://dx.doi.org/10.1371/journal.ppat.1002667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342949/
https://www.ncbi.nlm.nih.gov/pubmed/22570611
http://dx.doi.org/10.1371/journal.ppat.1002667

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