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The Lipopolysaccharide from Capnocytophaga canimorsus Reveals an Unexpected Role of the Core-Oligosaccharide in MD-2 Binding
Capnocytophaga canimorsus is a usual member of dog's mouths flora that causes rare but dramatic human infections after dog bites. We determined the structure of C. canimorsus lipid A. The main features are that it is penta-acylated and composed of a “hybrid backbone” lacking the 4′ phosphate an...
Autores principales: | Ittig, Simon, Lindner, Buko, Stenta, Marco, Manfredi, Pablo, Zdorovenko, Evelina, Knirel, Yuriy A., dal Peraro, Matteo, Cornelis, Guy R., Zähringer, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342949/ https://www.ncbi.nlm.nih.gov/pubmed/22570611 http://dx.doi.org/10.1371/journal.ppat.1002667 |
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