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Protective Activity of Streptococcus pneumoniae Spr1875 Protein Fragments Identified Using a Phage Displayed Genomic Library
There is considerable interest in pneumococcal protein antigens capable of inducing serotype-independent immunoprotection and of improving, thereby, existing vaccines. We report here on the immunogenic properties of a novel surface antigen encoded by ORF spr1875 in the R6 strain genome. An antigenic...
Autores principales: | Cardaci, Angela, Papasergi, Salvatore, Midiri, Angelina, Mancuso, Giuseppe, Domina, Maria, Cariccio, Veronica Lanza, Mandanici, Francesca, Galbo, Roberta, Passo, Carla Lo, Pernice, Ida, Donato, Paolo, Ricci, Susanna, Biondo, Carmelo, Teti, Giuseppe, Felici, Franco, Beninati, Concetta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343019/ https://www.ncbi.nlm.nih.gov/pubmed/22570729 http://dx.doi.org/10.1371/journal.pone.0036588 |
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