Stemness of the Organ of Corti Relates to the Epigenetic Status of Sox2 Enhancers

In the adult mammalian auditory epithelium, the organ of Corti, loss of sensory hair cells results in permanent hearing loss. The underlying cause for the lack of regenerative response is the depletion of otic progenitors in the cell pool of the sensory epithelium. Here, we show that an increase in...

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Detalles Bibliográficos
Autores principales: Waldhaus, Jörg, Cimerman, Jelka, Gohlke, Henning, Ehrich, Mathias, Müller, Marcus, Löwenheim, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343037/
https://www.ncbi.nlm.nih.gov/pubmed/22570694
http://dx.doi.org/10.1371/journal.pone.0036066

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