Disparate In Vivo Efficacy of FTY720 in Xenograft Models of Philadelphia Positive and Negative B-lineage Acute Lymphoblastic Leukemia

Most patients with acute lymphoblastic leukemia (ALL) respond well to standard chemotherapy-based treatments. However a significant proportion of patients, particularly adult patients, relapse with the majority dying of leukemia. FTY720 is an immunosuppressive drug that was recently approved for the...

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Detalles Bibliográficos
Autores principales: Wallington-Beddoe, Craig T., Don, Anthony S., Hewson, John, Qiao, Qiao, Papa, Rachael A., Lock, Richard B., Bradstock, Kenneth F., Bendall, Linda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343039/
https://www.ncbi.nlm.nih.gov/pubmed/22570713
http://dx.doi.org/10.1371/journal.pone.0036429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343039/
https://www.ncbi.nlm.nih.gov/pubmed/22570713
http://dx.doi.org/10.1371/journal.pone.0036429

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