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The Rac GTP Exchange Factor TIAM-1 Acts with CDC-42 and the Guidance Receptor UNC-40/DCC in Neuronal Protrusion and Axon Guidance

The mechanisms linking guidance receptors to cytoskeletal dynamics in the growth cone during axon extension remain mysterious. The Rho-family GTPases Rac and CDC-42 are key regulators of growth cone lamellipodia and filopodia formation, yet little is understood about how these molecules interact in...

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Detalles Bibliográficos
Autores principales:	Demarco, Rafael S., Struckhoff, Eric C., Lundquist, Erik A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343084/ https://www.ncbi.nlm.nih.gov/pubmed/22570618 http://dx.doi.org/10.1371/journal.pgen.1002665

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