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Selective Blockade of Trypanosomatid Protein Synthesis by a Recombinant Antibody Anti-Trypanosoma cruzi P2β Protein
The ribosomal P proteins are located on the stalk of the ribosomal large subunit and play a critical role during the elongation step of protein synthesis. The single chain recombinant antibody C5 (scFv C5) directed against the C-terminal region of the Trypanosoma cruzi P2β protein (TcP2β) recognizes...
Autores principales: | Juri Ayub, Maximiliano, Nyambega, Benson, Simonetti, Leandro, Duffy, Tomas, Longhi, Silvia A., Gómez, Karina A., Hoebeke, Johan, Levin, Mariano J., Smulski, Cristian R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343115/ https://www.ncbi.nlm.nih.gov/pubmed/22570698 http://dx.doi.org/10.1371/journal.pone.0036233 |
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