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Are Long-Range Structural Correlations Behind the Aggregration Phenomena of Polyglutamine Diseases?
We have characterized the conformational ensembles of polyglutamine [Image: see text] peptides of various lengths [Image: see text] (ranging from [Image: see text] to [Image: see text]), both with and without the presence of a C-terminal polyproline hexapeptide. For this, we used state-of-the-art mo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343152/ https://www.ncbi.nlm.nih.gov/pubmed/22577357 http://dx.doi.org/10.1371/journal.pcbi.1002501 |