Enantioselective supramolecular devices in the gas phase. Resorcin[4]arene as a model system

This review describes the state-of-art in the field of the gas-phase reactivity of diastereomeric complexes formed between a chiral artificial receptor and a biologically active molecule. The presented experimental approach is a ligand-displacement reaction carried out in a nano ESI-FT-ICR instrumen...

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Detalles Bibliográficos
Autores principales: Fraschetti, Caterina, Letzel, Matthias C, Filippi, Antonello, Speranza, Maurizio, Mattay, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343281/
https://www.ncbi.nlm.nih.gov/pubmed/22563353
http://dx.doi.org/10.3762/bjoc.8.62
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author Fraschetti, Caterina
Letzel, Matthias C
Filippi, Antonello
Speranza, Maurizio
Mattay, Jochen
author_facet Fraschetti, Caterina
Letzel, Matthias C
Filippi, Antonello
Speranza, Maurizio
Mattay, Jochen
author_sort Fraschetti, Caterina
collection PubMed
description This review describes the state-of-art in the field of the gas-phase reactivity of diastereomeric complexes formed between a chiral artificial receptor and a biologically active molecule. The presented experimental approach is a ligand-displacement reaction carried out in a nano ESI-FT-ICR instrument, supported by a thermodynamic MS-study and molecular-mechanics and molecular-dynamics (MM/MD) computational techniques. The noncovalent ion–molecule complexes are ideal for the study of chiral recognition in the absence of complicating solvent and counterion effects.
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spelling pubmed-33432812012-05-04 Enantioselective supramolecular devices in the gas phase. Resorcin[4]arene as a model system Fraschetti, Caterina Letzel, Matthias C Filippi, Antonello Speranza, Maurizio Mattay, Jochen Beilstein J Org Chem Review This review describes the state-of-art in the field of the gas-phase reactivity of diastereomeric complexes formed between a chiral artificial receptor and a biologically active molecule. The presented experimental approach is a ligand-displacement reaction carried out in a nano ESI-FT-ICR instrument, supported by a thermodynamic MS-study and molecular-mechanics and molecular-dynamics (MM/MD) computational techniques. The noncovalent ion–molecule complexes are ideal for the study of chiral recognition in the absence of complicating solvent and counterion effects. Beilstein-Institut 2012-04-12 /pmc/articles/PMC3343281/ /pubmed/22563353 http://dx.doi.org/10.3762/bjoc.8.62 Text en Copyright © 2012, Fraschetti et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Review
Fraschetti, Caterina
Letzel, Matthias C
Filippi, Antonello
Speranza, Maurizio
Mattay, Jochen
Enantioselective supramolecular devices in the gas phase. Resorcin[4]arene as a model system
title Enantioselective supramolecular devices in the gas phase. Resorcin[4]arene as a model system
title_full Enantioselective supramolecular devices in the gas phase. Resorcin[4]arene as a model system
title_fullStr Enantioselective supramolecular devices in the gas phase. Resorcin[4]arene as a model system
title_full_unstemmed Enantioselective supramolecular devices in the gas phase. Resorcin[4]arene as a model system
title_short Enantioselective supramolecular devices in the gas phase. Resorcin[4]arene as a model system
title_sort enantioselective supramolecular devices in the gas phase. resorcin[4]arene as a model system
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343281/
https://www.ncbi.nlm.nih.gov/pubmed/22563353
http://dx.doi.org/10.3762/bjoc.8.62
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