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Organismal propagation in the absence of a functional telomerase pathway in Caenorhabditis elegans

To counteract replication-dependent telomere shortening most eukaryotic cells rely on the telomerase pathway, which is crucial for the maintenance of proliferative potential of germ and stem cell populations of multicellular organisms. Likewise, cancer cells usually engage the telomerase pathway for...

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Detalles Bibliográficos
Autores principales: Lackner, Daniel H, Raices, Marcela, Maruyama, Hugo, Haggblom, Candy, Karlseder, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343340/
https://www.ncbi.nlm.nih.gov/pubmed/22425786
http://dx.doi.org/10.1038/emboj.2012.61