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Organismal propagation in the absence of a functional telomerase pathway in Caenorhabditis elegans
To counteract replication-dependent telomere shortening most eukaryotic cells rely on the telomerase pathway, which is crucial for the maintenance of proliferative potential of germ and stem cell populations of multicellular organisms. Likewise, cancer cells usually engage the telomerase pathway for...
Autores principales: | Lackner, Daniel H, Raices, Marcela, Maruyama, Hugo, Haggblom, Candy, Karlseder, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343340/ https://www.ncbi.nlm.nih.gov/pubmed/22425786 http://dx.doi.org/10.1038/emboj.2012.61 |
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