Mitotic spindle orientation can direct cell fate and bias Notch activity in chick neural tube
Inheritance of apical membrane is proposed to maintain vertebrate neural stem cell proliferation. However, evidence for this is contradictory. Using direct clonal analysis and live imaging in chick neural tube, we show that divisions that separate apical and basal components generate an apical daugh...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343353/ https://www.ncbi.nlm.nih.gov/pubmed/22491029 http://dx.doi.org/10.1038/embor.2012.42 |