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Action of Molecular Switches in GPCRs - Theoretical and Experimental Studies

G protein coupled receptors (GPCRs), also called 7TM receptors, form a huge superfamily of membrane proteins that, upon activation by extracellular agonists, pass the signal to the cell interior. Ligands can bind either to extracellular N-terminus and loops (e.g. glutamate receptors) or to the bindi...

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Detalles Bibliográficos
Autores principales: Trzaskowski, B, Latek, D, Yuan, S, Ghoshdastider, U, Debinski, A, Filipek, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343417/
https://www.ncbi.nlm.nih.gov/pubmed/22300046
http://dx.doi.org/10.2174/092986712799320556