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Urinary Hypoxia-Inducible Factor-1alpha Levels Are Associated with Histologic Chronicity Changes and Renal Function in Patients with Lupus Nephritis

PURPOSE: Tubulointerstitial hypoxia in the kidney is considered a hallmark of injury and a mediator of the progression of tubulointerstitial fibrosis. Hypoxia-inducible factor-1alpha (HIF-1alpha), a master transcription factor in cellular adaptation to hypoxia, regulates a wide variety of genes, som...

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Detalles Bibliográficos
Autores principales:	Ma, Chunyang, Wei, Jiali, Zhan, Feng, Wang, Ru, Fu, Keying, Wan, Xiaoping, Li, Zhuori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Yonsei University College of Medicine 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343432/ https://www.ncbi.nlm.nih.gov/pubmed/22477004 http://dx.doi.org/10.3349/ymj.2012.53.3.587

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