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Galectin-8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

Autophagy defends the mammalian cytosol against bacterial infection.(1-3) Efficient pathogen engulfment is mediated by cargo-selecting autophagy adaptors that rely on unidentified pattern-recognition or danger receptors to label invading pathogens as autophagy cargo, typically by poly-ubiquitin coat...

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Detalles Bibliográficos
Autores principales: Thurston, Teresa L. M., Wandel, Michal P., von Muhlinen, Natalia, Foeglein, Ágnes, Randow, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343631/
https://www.ncbi.nlm.nih.gov/pubmed/22246324
http://dx.doi.org/10.1038/nature10744

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