Psoriasis Patients Are Enriched for Genetic Variants That Protect against HIV-1 Disease

An important paradigm in evolutionary genetics is that of a delicate balance between genetic variants that favorably boost host control of infection but which may unfavorably increase susceptibility to autoimmune disease. Here, we investigated whether patients with psoriasis, a common immune-mediate...

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Detalles Bibliográficos
Autores principales: Chen, Haoyan, Hayashi, Genki, Lai, Olivia Y., Dilthey, Alexander, Kuebler, Peter J., Wong, Tami V., Martin, Maureen P., Fernandez Vina, Marcelo A., McVean, Gil, Wabl, Matthias, Leslie, Kieron S., Maurer, Toby, Martin, Jeffrey N., Deeks, Steven G., Carrington, Mary, Bowcock, Anne M., Nixon, Douglas F., Liao, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343879/
https://www.ncbi.nlm.nih.gov/pubmed/22577363
http://dx.doi.org/10.1371/journal.pgen.1002514

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