4-[5-Amino-4-(4-fluoro­phen­yl)-3-(pyridin-4-yl)-1H-pyrazol-1-yl]benzo­nitrile

In the crystal structure of the title compound, C(21)H(14)FN(5), the pyrazole ring forms dihedral angles of 38.0 (1), 40.0 (1) and 28.5 (1)° with the directly attached 4-fluoro­phenyl, pyridine and benzonitrile rings, respectively. The crystal packing is characterized by N—H⋯N hydrogen bonds, which...

Descripción completa

Detalles Bibliográficos
Autores principales: Abu Thaher, Bassam, Koch, Pierre, Schollmeyer, Dieter, Laufer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343917/
https://www.ncbi.nlm.nih.gov/pubmed/22589998
http://dx.doi.org/10.1107/S160053681200877X
_version_ 1782231873889501184
author Abu Thaher, Bassam
Koch, Pierre
Schollmeyer, Dieter
Laufer, Stefan
author_facet Abu Thaher, Bassam
Koch, Pierre
Schollmeyer, Dieter
Laufer, Stefan
author_sort Abu Thaher, Bassam
collection PubMed
description In the crystal structure of the title compound, C(21)H(14)FN(5), the pyrazole ring forms dihedral angles of 38.0 (1), 40.0 (1) and 28.5 (1)° with the directly attached 4-fluoro­phenyl, pyridine and benzonitrile rings, respectively. The crystal packing is characterized by N—H⋯N hydrogen bonds, which result in a two-dimensional network parallel to the ac-plane.
format Online
Article
Text
id pubmed-3343917
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-33439172012-05-15 4-[5-Amino-4-(4-fluoro­phen­yl)-3-(pyridin-4-yl)-1H-pyrazol-1-yl]benzo­nitrile Abu Thaher, Bassam Koch, Pierre Schollmeyer, Dieter Laufer, Stefan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the crystal structure of the title compound, C(21)H(14)FN(5), the pyrazole ring forms dihedral angles of 38.0 (1), 40.0 (1) and 28.5 (1)° with the directly attached 4-fluoro­phenyl, pyridine and benzonitrile rings, respectively. The crystal packing is characterized by N—H⋯N hydrogen bonds, which result in a two-dimensional network parallel to the ac-plane. International Union of Crystallography 2012-03-03 /pmc/articles/PMC3343917/ /pubmed/22589998 http://dx.doi.org/10.1107/S160053681200877X Text en © Abu Thaher et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Abu Thaher, Bassam
Koch, Pierre
Schollmeyer, Dieter
Laufer, Stefan
4-[5-Amino-4-(4-fluoro­phen­yl)-3-(pyridin-4-yl)-1H-pyrazol-1-yl]benzo­nitrile
title 4-[5-Amino-4-(4-fluoro­phen­yl)-3-(pyridin-4-yl)-1H-pyrazol-1-yl]benzo­nitrile
title_full 4-[5-Amino-4-(4-fluoro­phen­yl)-3-(pyridin-4-yl)-1H-pyrazol-1-yl]benzo­nitrile
title_fullStr 4-[5-Amino-4-(4-fluoro­phen­yl)-3-(pyridin-4-yl)-1H-pyrazol-1-yl]benzo­nitrile
title_full_unstemmed 4-[5-Amino-4-(4-fluoro­phen­yl)-3-(pyridin-4-yl)-1H-pyrazol-1-yl]benzo­nitrile
title_short 4-[5-Amino-4-(4-fluoro­phen­yl)-3-(pyridin-4-yl)-1H-pyrazol-1-yl]benzo­nitrile
title_sort 4-[5-amino-4-(4-fluoro­phen­yl)-3-(pyridin-4-yl)-1h-pyrazol-1-yl]benzo­nitrile
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343917/
https://www.ncbi.nlm.nih.gov/pubmed/22589998
http://dx.doi.org/10.1107/S160053681200877X
work_keys_str_mv AT abuthaherbassam 45amino44fluorophenyl3pyridin4yl1hpyrazol1ylbenzonitrile
AT kochpierre 45amino44fluorophenyl3pyridin4yl1hpyrazol1ylbenzonitrile
AT schollmeyerdieter 45amino44fluorophenyl3pyridin4yl1hpyrazol1ylbenzonitrile
AT lauferstefan 45amino44fluorophenyl3pyridin4yl1hpyrazol1ylbenzonitrile

Ejemplares similares