Chlordiazepoxide dichloro­methane monosolvate

In the title compound (systematic name: 7-chloro-2-methyl­amino-5-phenyl-3H-1,4-benzodiazepine 4-oxide dichloro­meth­ane monosolvate), C(16)H(14)ClN(3)O·CH(2)Cl(2), the seven-membered ring adopts a boat conformation with the CH(2) group as the prow and the two aromatic C atoms as the stern. The dihe...

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Detalles Bibliográficos
Autor principal: Fischer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343976/
https://www.ncbi.nlm.nih.gov/pubmed/22589885
http://dx.doi.org/10.1107/S1600536812009695
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author Fischer, Andreas
author_facet Fischer, Andreas
author_sort Fischer, Andreas
collection PubMed
description In the title compound (systematic name: 7-chloro-2-methyl­amino-5-phenyl-3H-1,4-benzodiazepine 4-oxide dichloro­meth­ane monosolvate), C(16)H(14)ClN(3)O·CH(2)Cl(2), the seven-membered ring adopts a boat conformation with the CH(2) group as the prow and the two aromatic C atoms as the stern. The dihedral angle between the benzene rings is 75.25 (6)°. The crystal structure features centrosymmetric pairs of chlordiazepoxide mol­ecules linked by pairs of N—H⋯O hydrogen bonds, which generate R (2) (2)(12) loops.
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spelling pubmed-33439762012-05-15 Chlordiazepoxide dichloro­methane monosolvate Fischer, Andreas Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound (systematic name: 7-chloro-2-methyl­amino-5-phenyl-3H-1,4-benzodiazepine 4-oxide dichloro­meth­ane monosolvate), C(16)H(14)ClN(3)O·CH(2)Cl(2), the seven-membered ring adopts a boat conformation with the CH(2) group as the prow and the two aromatic C atoms as the stern. The dihedral angle between the benzene rings is 75.25 (6)°. The crystal structure features centrosymmetric pairs of chlordiazepoxide mol­ecules linked by pairs of N—H⋯O hydrogen bonds, which generate R (2) (2)(12) loops. International Union of Crystallography 2012-03-10 /pmc/articles/PMC3343976/ /pubmed/22589885 http://dx.doi.org/10.1107/S1600536812009695 Text en © Andreas Fischer 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fischer, Andreas
Chlordiazepoxide dichloro­methane monosolvate
title Chlordiazepoxide dichloro­methane monosolvate
title_full Chlordiazepoxide dichloro­methane monosolvate
title_fullStr Chlordiazepoxide dichloro­methane monosolvate
title_full_unstemmed Chlordiazepoxide dichloro­methane monosolvate
title_short Chlordiazepoxide dichloro­methane monosolvate
title_sort chlordiazepoxide dichloro­methane monosolvate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343976/
https://www.ncbi.nlm.nih.gov/pubmed/22589885
http://dx.doi.org/10.1107/S1600536812009695
work_keys_str_mv AT fischerandreas chlordiazepoxidedichloromethanemonosolvate

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